Hydrochloric Acid → ethyl 3-hydroxy-3-{6-[(methylamino)carbonyl]-2-naphthyl}-3-(1-trityl-1H-imidazol-4-yl)propanoate
Reaction equation
[Br:6][CH2:7][C:8](=[O:9])[O:10][CH2:11][CH3:12].[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[CH3:19][NH:20][C:21](=[O:22])[c:23]1[cH:24][c:25]2[cH:26][cH:27][c:28]([C:33](=[O:34])[c:35]3[n:36][cH:37][n:38]([C:40]([c:41]4[cH:42][cH:43][cH:44][cH:45][cH:46]4)([c:47]4[cH:48][cH:49][cH:50][cH:51][cH:52]4)[c:53]4[cH:54][cH:55][cH:56][cH:57][cH:58]4)[cH:39]3)[cH:29][c:30]2[cH:31][cH:32]1.[CH3:65][CH2:66][O:67][C:68](=[O:69])[CH3:70].[Cl:1][Si:2]([CH3:3])([CH3:4])[CH3:5].[ClH:59].[Zn:71].[cH:13]1[cH:14][cH:15][n:16][cH:17][cH:18]1>>[CH2:7]([C:8](=[O:9])[O:10][CH2:11][CH3:12])[C:33]([c:28]1[cH:27][cH:26][c:25]2[cH:24][c:23]([C:21]([NH:20][CH3:19])=[O:22])[cH:32][cH:31][c:30]2[cH:29]1)([OH:34])[c:35]1[n:36][cH:37][n:38]([C:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:39]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-a51da08fb8024242b7435cd46ad254ad
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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