1,2-Dichloroethane → 1-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic Acid [4-(6-aminofuro[3,2-c]pyridin-7-yloxymethyl)phenyl]amide

HRID 1121148Notes

Reaction equation

HRID 1121148 reaction equation
[CH3:38][CH2:39][OH:40].[Cl-:41].[Cl:44][CH2:45][CH2:46][Cl:47].[Fe:43].[N+:1]([O-:2])(=[O:3])[c:4]1[c:5]([O:13][CH2:14][c:15]2[cH:16][cH:17][c:18]([NH:21][C:22](=[O:23])[c:24]3[c:25](=[O:37])[n:26](-[c:30]4[cH:31][cH:32][c:33]([F:36])[cH:34][cH:35]4)[cH:27][cH:28][cH:29]3)[cH:19][cH:20]2)[c:6]2[c:7]([cH:8][n:9]1)[cH:10][cH:11][o:12]2.[NH4+:42]>>[NH2:1][c:4]1[c:5]([O:13][CH2:14][c:15]2[cH:16][cH:17][c:18]([NH:21][C:22](=[O:23])[c:24]3[c:25](=[O:37])[n:26](-[c:30]4[cH:31][cH:32][c:33]([F:36])[cH:34][cH:35]4)[cH:27][cH:28][cH:29]3)[cH:19][cH:20]2)[c:6]2[c:7]([cH:8][n:9]1)[cH:10][cH:11][o:12]2

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 223AmmoniumHCID 312ChlorideHCID 702EthanolHCID 23925IronHCID 578125811-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid [4-(6-nitrofuro[3,2-c]pyridin-7-yloxymethyl)phenyl]amide

Product 1

HCID 578126951-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic Acid [4-(6-aminofuro[3,2-c]pyridin-7-yloxymethyl)phenyl]amide

Sources & evidence

ORD record
ord-2ebd0dc4f31b450cb648a2e17bb48c05
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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