Benzaldehyde → Ethyl 2,2-difluoro-3-hydroxy-3-phenylpropanoate
Reaction equation
[Br:9][C:10]([C:11](=[O:12])[O:13][CH2:14][CH3:15])([F:16])[F:17].[CH2:24]([O:25][CH2:26][CH3:27])[CH3:28].[CH:1](=[O:2])[c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1.[ClH:18].[O:19]1[CH2:20][CH2:21][CH2:22][CH2:23]1.[Zn:29]>>[CH:1]([OH:2])([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[C:10]([C:11](=[O:12])[O:13][CH2:14][CH3:15])([F:16])[F:17]Participants
7
Sources & evidence
- ORD record
- ord-b26432ec4c4a4476b199b76132b6ed4e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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