Chloroform → 4-[(3-Chloro-4-methoxyphenyl)methylamino]-2-[2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carbaldehyde
Reaction equation
[CH3:1][S:2][c:3]1[n:4][cH:5][c:6]([CH:20]=[O:21])[c:7]([NH:9][CH2:10][c:11]2[cH:12][c:13]([Cl:19])[c:14]([O:17][CH3:18])[cH:15][cH:16]2)[n:8]1.[CH3:40][CH2:41][N:42]([CH2:43][CH3:44])[CH2:45][CH3:46].[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[CH:47]([Cl:48])([Cl:49])[Cl:50].[Cl:22][c:23]1[cH:24][cH:25][cH:26][c:27]([C:28]([O:29][OH:30])=[O:31])[cH:32]1.[NH:33]1[CH:34]([CH2:35][OH:36])[CH2:37][CH2:38][CH2:39]1>>[c:3]1([N:33]2[CH:34]([CH2:35][OH:36])[CH2:37][CH2:38][CH2:39]2)[n:4][cH:5][c:6]([CH:20]=[O:21])[c:7]([NH:9][CH2:10][c:11]2[cH:12][c:13]([Cl:19])[c:14]([O:17][CH3:18])[cH:15][cH:16]2)[n:8]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5d065f7851974a5c80574b536ec88c01
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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