Phthalimide → 1-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-2-phenyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[C:10]2([CH2:14][OH:15])[CH2:11][CH:12]2[CH2:13]1.[CH2:52]1[O:53][CH2:54][CH2:55][CH2:56]1.[O:41]=[C:42]1[NH:43][C:44](=[O:45])[c:46]2[cH:47][cH:48][cH:49][cH:50][c:51]21.[c:22]1([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[C:10]2([CH2:14][N:43]3[C:42](=[O:41])[c:51]4[c:46]([cH:47][cH:48][cH:49][cH:50]4)[C:44]3=[O:45])[CH2:11][CH:12]2[CH2:13]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-47c913306f11468ebd1c06b72ff93b5f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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