Hydrochloric Acid → 5-Bromo-3-[5-(1-ethylamino-1-methyl-ethyl)-pyridin-2-ylamino]-1-methyl-1H-pyridin-2-one

HRID 1125597Notes

Reaction equation

[BH3:27].[Br:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[cH:12][cH:13][c:14]([C:17]([CH3:18])([CH3:19])[NH:20][C:21]([CH3:22])=[O:23])[cH:15][n:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:24][S:25][CH3:26].[ClH:28].[Na+:30].[OH-:29].[OH2:36]>>[Br:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[cH:12][cH:13][c:14]([C:17]([CH3:18])([CH3:19])[NH:20][CH2:21][CH3:22])[cH:15][n:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1

Participants

Reactant 8

HCID 313Hydrochloric Acid

HCID 923Sodium ion

HCID 961Hydroxide

HCID 962Water

HCID 1068Dimethyl Sulfide

HCID 6331Borane

HCID 8028Tetrahydrofuran

HCID 59473804N-(2-(6-(5-bromo-1-methyl-2-oxo-1,2-dihydropyridin-3-ylamino)pyridin-3-yl)propan-2-yl)acetamide

Product 1

HCID 594738195-Bromo-3-[5-(1-ethylamino-1-methyl-ethyl)-pyridin-2-ylamino]-1-methyl-1H-pyridin-2-one

Sources & evidence

ORD record: ord-07a9a634504c42fe8ceea703b6691d4c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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