4-Bromoanisole → 5-Chloro-3-hydroxy-3-(4-methoxyphenyl)-1,3-dihydro-2H-indol-2-one
Reaction equation
[Br:2][c:3]1[cH:4][cH:5][c:6]([O:9][CH3:10])[cH:7][cH:8]1.[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[Cl:11][c:12]1[cH:13][c:14]2[c:18]([cH:19][cH:20]1)[NH:17][C:16](=[O:21])[C:15]2=[O:22].[Mg:1]>>[c:3]1([C:15]2([OH:22])[c:14]3[cH:13][c:12]([Cl:11])[cH:20][cH:19][c:18]3[NH:17][C:16]2=[O:21])[cH:4][cH:5][c:6]([O:9][CH3:10])[cH:7][cH:8]1Participants
5
Sources & evidence
- ORD record
- ord-86e4c044478343d3b731ec1ffc011c15
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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