反应详情

45 g (247 mmol) of trichloroacetyl chloride and 100 ml of ethyl ether were introduced into a three-necked flask. A solution of 15.4 g (230 mmol) of pyrrole in 100 ml of ethyl ether was added dropwise and the mixture was stirred at room temperature for one hour, then a solution of 20 g of potassium carbonate in 60 ml of water was added slowly. The organic phase was decanted off, dried over magnesium sulfate, evaporated, the residue triturated in hexane and filtered. 42.7 g (87%) of the expected compound of melting point 78°-79° C. were recovered.

1. customThe organic phase was decanted off
2. dry with materialdried over magnesium sulfate
3. customevaporated
4. customthe residue triturated in hexane
5. filtrationfiltered
6. custom42.7 g (87%) of the expected compound of melting point 78°-79° C. were recovered