Water → 1-(5-Tert-butylisoxazol-3-yl)-3-(5-(6,7-dimethoxyquinazolin-4-yloxy)-2,4-difluorophenyl)urea
Reaction equation
[C:34]([CH3:35])([CH3:36])([CH3:37])[c:38]1[cH:39][c:40]([NH:43][C:44]([O:45][c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)=[O:46])[n:41][o:42]1.[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[c:17]([F:24])[cH:18][c:19]([F:23])[c:20]([NH2:21])[cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[CH3:59][N:60]([c:61]1[cH:62][cH:63][n:64][cH:65][cH:66]1)[CH3:67].[CH:25]([N:26]([CH2:27][CH3:28])[CH:29]([CH3:30])[CH3:31])([CH3:32])[CH3:33].[OH2:53]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[c:17]([F:24])[cH:18][c:19]([F:23])[c:20]([NH:21][C:44]([NH:43][c:40]4[cH:39][c:38]([C:34]([CH3:35])([CH3:36])[CH3:37])[o:42][n:41]4)=[O:45])[cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-c29b05f544c74fdfa8b8882eb9f1d4b5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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