Dichloromethane → Benzyl 4-(hydroxymethyl)piperidine-1-carboxylate

HRID 1127756Notes

Reaction equation

HRID 1127756 reaction equation
[CH2:29]([Cl:30])[Cl:31].[CH3:32][CH2:33][O:34][C:35](=[O:36])[CH3:37].[CH:1]([N:2]([CH2:3][CH3:4])[CH:5]([CH3:6])[CH3:7])([CH3:8])[CH3:9].[Cl:18][C:19](=[O:20])[O:21][CH2:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[OH:10][CH2:11][CH:12]1[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1>>[OH:10][CH2:11][CH:12]1[CH2:13][CH2:14][N:15]([C:19](=[O:20])[O:21][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:16][CH2:17]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 10387Benzyl chloroformateHCID 81531DiisopropylethylamineHCID 4207714-Piperidinemethanol

Product 1

HCID 736490Benzyl 4-(hydroxymethyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-724fca1f05e54381af88d0d81895332d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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