Hydrochloric Acid → 4-(Phenylethynyl)pyridine

HRID 1128135Notes

Reaction equation

HRID 1128135 reaction equation
[Br:2][c:3]1[cH:4][cH:5][n:6][cH:7][cH:8]1.[CH3:9][CH2:10][N:11]([CH2:12][CH3:13])[CH2:14][CH3:15].[ClH:1].[O:24]=[CH:25][N:26]([CH3:27])[CH3:28].[c:16]1([C:22]#[CH:23])[cH:17][cH:18][cH:19][cH:20][cH:21]1.[cH:29]1[cH:30][cH:31][c:32]([P:33]([Pd:34]([P:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)([P:54]([c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[P:73]([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)([c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)[c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)[c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[cH:104][cH:105]1>>[c:3]1([C:23]#[C:22][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[cH:4][cH:5][n:6][cH:7][cH:8]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 8471TriethylamineHCID 10821PhenylacetyleneHCID 142684-BromopyridineHCID 178420554HCID 178420554, compound

Product 1

HCID 3521724-(Phenylethynyl)pyridine

Sources & evidence

ORD record
ord-1c7934c8a4ed4fc996919cc3b2a80f4e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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