Tetrahydrofuran → 5-Bromo-2-(4-methylpiperazin-1-yl)pyridine
Reaction equation
[CH2:16]1[O:17][CH2:18][CH2:19][CH2:20]1.[CH3:21][CH2:22][O:23][C:24]([CH3:25])=[O:26].[CH3:9][N:10]1[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]1.[F:1][c:2]1[n:3][cH:4][c:5]([Br:8])[cH:6][cH:7]1>>[c:2]1([N:13]2[CH2:12][CH2:11][N:10]([CH3:9])[CH2:15][CH2:14]2)[n:3][cH:4][c:5]([Br:8])[cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-abf208879cb448a0904e33098bd3c00b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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