Water → N-(1-methoxycarbonylpiperidin-4-yl)-N'-(4-fluorophenyl)urea

HRID 1128971Notes

Reaction equation

HRID 1128971 reaction equation
[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[CH:29]([O:30][CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[Cl:24][C:25](=[O:26])[O:27][CH3:28].[NH:1]1[CH2:2][CH2:3][CH:4]([NH:7][C:8](=[O:9])[NH:10][c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[CH2:5][CH2:6]1.[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH2:47].[cH:18]1[cH:19][cH:20][n:21][cH:22][cH:23]1>>[N:1]1([C:25](=[O:26])[O:27][CH3:28])[CH2:2][CH2:3][CH:4]([NH:7][C:8](=[O:9])[NH:10][c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[CH2:5][CH2:6]1

Participants

8

Reactant 7

HCID 962WaterHCID 1049PyridineHCID 6586Methyl chloroformateHCID 7914Diisopropyl EtherHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 16781536283167-30-6

Product 1

HCID 9796177N-(1-methoxycarbonylpiperidin-4-yl)-N'-(4-fluorophenyl)urea

Sources & evidence

ORD record
ord-e4495cd2ac9f42859b1ae859e7de3c72
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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