Isopropanol → 2-(3,4-Dihydroxypyrrolidin-1-yl)-4-(3-fluorophenyl)-6-methoxyquinoline-3-carbonitrile
Reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:37][CH:38]([OH:39])[CH3:40].[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46].[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7]([O:21][CH3:22])[cH:8][c:9]2[c:10](-[c:14]2[cH:15][c:16]([F:20])[cH:17][cH:18][cH:19]2)[c:11]1[C:12]#[N:13].[OH:23][CH:24]1[CH2:25][NH:26][CH2:27][CH:28]1[OH:29]>>[c:2]1([N:26]2[CH2:25][CH:24]([OH:23])[CH:28]([OH:29])[CH2:27]2)[n:3][c:4]2[cH:5][cH:6][c:7]([O:21][CH3:22])[cH:8][c:9]2[c:10](-[c:14]2[cH:15][c:16]([F:20])[cH:17][cH:18][cH:19]2)[c:11]1[C:12]#[N:13]Participants
6
Sources & evidence
- ORD record
- ord-edccc87201b74a2d81b52f01b13b247a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…