Ammonium → Tert-butyl 4-{2-[(4-benzyloxy-5'-isopropyl-2'-methoxy-biphenyl-2-ylmethyl)-(3,5-bis-trifluoromethyl-benzyl)-amino]-pyrimidin-5-yloxy}-butyrate
Reaction equation
[CH2:34]([c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1)[O:41][c:42]1[cH:43][c:44]([CH2:59][Cl:60])[c:45](-[c:48]2[c:49]([O:57][CH3:58])[cH:50][cH:51][c:52]([CH:54]([CH3:55])[CH3:56])[cH:53]2)[cH:46][cH:47]1.[CH3:65][N:66]([CH3:67])[CH:68]=[O:69].[CH3:70][CH2:71][O:72][C:73](=[O:74])[CH3:75].[Cl-:63].[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][NH:7][c:8]2[n:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:12][n:13]2)[cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]1)([F:32])[F:33].[H-:61].[NH4+:64].[Na+:62]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]([c:8]2[n:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:12][n:13]2)[CH2:59][c:44]2[cH:43][c:42]([O:41][CH2:34][c:35]3[cH:36][cH:37][cH:38][cH:39][cH:40]3)[cH:47][cH:46][c:45]2-[c:48]2[c:49]([O:57][CH3:58])[cH:50][cH:51][c:52]([CH:54]([CH3:55])[CH3:56])[cH:53]2)[cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]1)([F:32])[F:33]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-7636158bacdb4d919ca22864571557f0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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