Ammonium → 4-Methyl-2-(4-tributylstannanyl-imidazol-1-yl)-6-(4-trifluoromethyl-phenyl)-pyrimidine

HRID 1134511Notes

Reaction equation

HRID 1134511 reaction equation
[CH2:31]([CH2:32][CH2:33][CH3:34])[Sn:35]([CH2:36][CH2:37][CH2:38][CH3:39])([CH2:40][CH2:41][CH2:42][CH3:43])[Cl:44].[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[CH:27]([Mg+:28])([CH3:29])[CH3:30].[Cl-:24].[Cl-:26].[Cl-:45].[I:1][c:2]1[n:3][cH:4][n:5](-[c:7]2[n:8][c:9](-[c:14]3[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]3)[cH:10][c:11]([CH3:13])[n:12]2)[cH:6]1.[Li+:25].[NH4+:46]>>[c:2]1([Sn:35]([CH2:31][CH2:32][CH2:33][CH3:34])([CH2:36][CH2:37][CH2:38][CH3:39])[CH2:40][CH2:41][CH2:42][CH3:43])[n:3][cH:4][n:5](-[c:7]2[n:8][c:9](-[c:14]3[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]3)[cH:10][c:11]([CH3:13])[n:12]2)[cH:6]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312Chloride3×HCID 8028TetrahydrofuranHCID 15096Tributyltin ChlorideHCID 28486Lithium ionHCID 574687852-(4-Iodo-imidazol-1-yl)-4-methyl-6-(4-trifluoromethyl-phenyl)-pyrimidineHCID 178461726HCID 178461726, compound

Product 1

HCID 574688294-Methyl-2-(4-tributylstannanyl-imidazol-1-yl)-6-(4-trifluoromethyl-phenyl)-pyrimidine

Sources & evidence

ORD record
ord-072071d8361c40528f3067db26408b10
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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