Ammonia → 1-Boc-3-ethynyl-3-hydroxypiperidine
Reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[N:19]1[CH2:20][C:21](=[O:25])[CH2:22][CH2:23][CH2:24]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38].[CH3:6][Si:7]([CH3:8])([CH3:9])[C:10]#[CH:11].[Cl-:26].[NH3:27].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[C:10](#[CH:11])[C:21]1([OH:25])[CH2:20][N:19]([C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[CH2:24][CH2:23][CH2:22]1Participants
8
Sources & evidence
- ORD record
- ord-d72abfd525174b1fa636154bb1518d38
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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