Hydrochloric Acid → (+/-)-2'-Oxo-3,4-dihydro-1H-spiro[naphthalene-2,3'-pyrrolidine]-6-carboxylic acid
Reaction equation
[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[ClH:22].[Li+:20].[O:1]=[C:2]1[NH:3][CH2:4][CH2:5][C:6]12[CH2:7][c:8]1[cH:9][cH:10][c:11]([C:16](=[O:17])[O:18][CH3:19])[cH:12][c:13]1[CH2:14][CH2:15]2.[OH-:21].[OH2:28]>>[O:1]=[C:2]1[NH:3][CH2:4][CH2:5][C:6]12[CH2:7][c:8]1[cH:9][cH:10][c:11]([C:16](=[O:17])[OH:18])[cH:12][c:13]1[CH2:14][CH2:15]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-657bc85f9bad4f1590e439fed4c6fb15
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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