Sodium ion → 3-Tert-butyloxycarbonyl-6-(3-chloropropyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole

HRID 1138272Notes

Reaction equation

HRID 1138272 reaction equation
[Br:29][CH2:30][CH2:31][CH2:32][Cl:33].[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][c:13]2[nH:14][c:15]3[cH:16][cH:17][cH:18][cH:19][c:20]3[c:21]2[CH2:22][CH2:23]1.[CH3:34][CH2:35][O:36][C:37]([CH3:38])=[O:39].[H-:1].[Na+:2].[O:24]=[CH:25][N:26]([CH3:27])[CH3:28]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][c:13]2[n:14]([CH2:30][CH2:31][CH2:32][Cl:33])[c:15]3[cH:16][cH:17][cH:18][cH:19][c:20]3[c:21]2[CH2:22][CH2:23]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 6228DimethylformamideHCID 80061-Bromo-3-chloropropaneHCID 8857Ethyl AcetateHCID 166653HydrideHCID 22396759tert-butyl 1,4,5,6-tetrahydroazepino[4,5-b]indole-3(2H)-carboxylate

Product 1

HCID 223966303-Tert-butyloxycarbonyl-6-(3-chloropropyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole

Sources & evidence

ORD record
ord-95c318f2c3a240c1952121fdc20c6d27
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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