Phthalimide → tert-Butyl alpha-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]-3-(2-methylpropyl)-2-oxo-1-(2-phenylethyl)-3-pyrrolidineacetate
Reaction equation
[CH2:72]1[O:73][CH2:74][CH2:75][CH2:76]1.[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[O:61]=[C:62]1[NH:63][C:64](=[O:65])[c:66]2[cH:67][cH:68][cH:69][cH:70][c:71]21.[OH:13][CH2:14][CH2:15][CH:16]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[C:24]1([CH2:38][CH:39]([CH3:40])[CH3:41])[C:25](=[O:37])[N:26]([CH2:29][CH2:30][c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH2:27][CH2:28]1.[c:42]1([P:43]([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[cH:56][cH:57][cH:58][cH:59][cH:60]1>>[CH2:14]([CH2:15][CH:16]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[C:24]1([CH2:38][CH:39]([CH3:40])[CH3:41])[C:25](=[O:37])[N:26]([CH2:29][CH2:30][c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH2:27][CH2:28]1)[N:63]1[C:62](=[O:61])[c:71]2[c:66]([cH:67][cH:68][cH:69][cH:70]2)[C:64]1=[O:65]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-da6378d69f934073a1e2a20d0afa548c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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