Sulfuric Acid → 2-chloro-5-(hydroxymethyl)Benzenesulfonamide

HRID 1138877Notes

Reaction equation

HRID 1138877 reaction equation
[CH2:1]1[O:2][CH2:3][CH2:4][CH2:5]1.[CH3:21][CH:22]([CH2:23][AlH:24][CH2:25][CH:26]([CH3:27])[CH3:28])[CH3:29].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[Cl:6][c:7]1[c:8]([S:17]([NH2:18])(=[O:19])=[O:20])[cH:9][c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][cH:16]1.[S:30](=[O:31])(=[O:32])([OH:33])[OH:34]>>[Cl:6][c:7]1[c:8]([S:17]([NH2:18])(=[O:19])=[O:20])[cH:9][c:10]([CH2:11][OH:12])[cH:15][cH:16]1

Participants

6

Reactant 5

HCID 1118Sulfuric AcidHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 14487Diisobutylaluminum hydrideHCID 4277179Methyl 4-chloro-3-sulfamoylbenzoate

Product 1

HCID 183743812-chloro-5-(hydroxymethyl)Benzenesulfonamide

Sources & evidence

ORD record
ord-53ba3253ee76422f8a8751460a956817
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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