1,2-Dichloroethane → 3-bromo-N-[1-[4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]benzamide
Reaction equation
[Br:25][c:26]1[cH:27][c:28]([C:29](=[O:30])[OH:31])[cH:32][cH:33][cH:34]1.[CH2:45]([Cl:46])[CH2:47][Cl:48].[CH2:56]([Cl:57])[Cl:58].[CH3:49][CH2:50][N:51]([CH2:52][CH3:53])[CH2:54][CH3:55].[ClH:24].[NH2:1][CH:2]([C:3](=[O:4])[N:5]1[CH2:6][C:7]([CH3:19])([CH3:20])[C:8]([OH:11])([c:12]2[cH:13][cH:14][c:15]([Cl:18])[cH:16][cH:17]2)[CH2:9][CH2:10]1)[CH:21]([CH3:22])[CH3:23].[OH:35][n:36]1[c:37]2[c:38]([cH:39][cH:40][cH:41][cH:42]2)[n:43][n:44]1>>[NH:1]([CH:2]([C:3](=[O:4])[N:5]1[CH2:6][C:7]([CH3:19])([CH3:20])[C:8]([OH:11])([c:12]2[cH:13][cH:14][c:15]([Cl:18])[cH:16][cH:17]2)[CH2:9][CH2:10]1)[CH:21]([CH3:22])[CH3:23])[C:29]([c:28]1[cH:27][c:26]([Br:25])[cH:34][cH:33][cH:32]1)=[O:30]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b3d0dfc009734d8098c81a029947879d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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