Chloride → ethyl (2RS,3RS)-3-(4-fluorophenyl)-3-hydroxy-2-((5-(trifluoromethyl)-2-furanyl)methyl)propionate
Reaction equation
[BH4-:1].[CH3:29][CH2:30][O:31][CH2:32][CH3:33].[Cl-:34].[Cl-:36].[ClH:28].[F:3][c:4]1[cH:5][cH:6][c:7]([C:10]([CH:11]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[CH2:17][c:18]2[o:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]2)=[O:27])[cH:8][cH:9]1.[Na+:2].[Zn+2:35]>>[F:3][c:4]1[cH:5][cH:6][c:7]([CH:10]([CH:11]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[CH2:17][c:18]2[o:19][c:20]([C:23]([F:24])([F:25])[F:26])[cH:21][cH:22]2)[OH:27])[cH:8][cH:9]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-7ce2a7c64e484ebda2730da9c0552ff2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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