Nitrogen → 8-(1-Ethyl-propyl)-2,6-dimethyl-3-(4-methyl-oxazol-5-yl)-imidazo[1,2-b]pyridazine

HRID 1141508Notes

Reaction equation

HRID 1141508 reaction equation
[C:43](=[O:44])([O-:45])[O-:46].[CH2:1]([CH3:2])[CH:3]([CH2:4][CH3:5])[c:6]1[c:7]2[n:8]([n:9][c:10]([CH3:12])[cH:11]1)[c:13]([I:17])[c:14]([CH3:16])[n:15]2.[CH3:18][c:19]1[n:20][cH:21][o:22][cH:23]1.[Cs+:47].[Cs+:48].[N:49]#[N:50].[O:52]=[CH:53][N:54]([CH3:55])[CH3:56].[OH2:51].[c:24]1([P:25]([c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[cH:38][cH:39][cH:40][cH:41][cH:42]1>>[CH2:1]([CH3:2])[CH:3]([CH2:4][CH3:5])[c:6]1[c:7]2[n:8]([n:9][c:10]([CH3:12])[cH:11]1)[c:13](-[c:23]1[c:19]([CH3:18])[n:20][cH:21][o:22]1)[c:14]([CH3:16])[n:15]2

Participants

9

Reactant 8

HCID 947NitrogenHCID 962WaterHCID 6228DimethylformamideHCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 696634-MethyloxazoleHCID 104967Cesium cation2×HCID 577526818-(1-Ethyl-propyl)-3-iodo-2,6-dimethyl-imidazo[1,2-b]pyridazine

Product 1

HCID 579329208-(1-Ethyl-propyl)-2,6-dimethyl-3-(4-methyl-oxazol-5-yl)-imidazo[1,2-b]pyridazine

Sources & evidence

ORD record
ord-1f44e4e70dd043cda4b04c12e1e33e5e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…