Hydrochloric Acid → 4-{1-[1-(ethylsulfonyl)-3-(fluoromethyl)azetidin-3-yl]-1H-pyrazol-4-yl}-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][O:41][CH2:42]1.[CH2:53]([CH3:54])[S:55](=[O:56])(=[O:57])[Cl:58].[CH3:43][C:44]#[N:45].[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[ClH:36].[F:1][CH2:2][C:3]1([n:14]2[n:15][cH:16][c:17](-[c:19]3[c:20]4[c:21]([n:22][cH:23][n:24]3)[n:25]([CH2:28][O:29][CH2:30][CH2:31][Si:32]([CH3:33])([CH3:34])[CH3:35])[cH:26][cH:27]4)[cH:18]2)[CH2:4][N:5]([C:7]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:13])[CH2:6]1>>[F:1][CH2:2][C:3]1([n:14]2[n:15][cH:16][c:17](-[c:19]3[c:20]4[c:21]([n:22][cH:23][n:24]3)[n:25]([CH2:28][O:29][CH2:30][CH2:31][Si:32]([CH3:33])([CH3:34])[CH3:35])[cH:26][cH:27]4)[cH:18]2)[CH2:4][N:5]([S:55]([CH2:53][CH3:54])(=[O:56])=[O:57])[CH2:6]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9bebc0bc93144e5f948f6a3170bf3019
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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