Hydrochloric Acid → 6-(3-Chloro-4-fluorobenzyl)-4-methoxy-2-methyl-3,5-dioxo-2,3,5,6,7,8-hexahydro-2,6-naphthyridine-1-carboxylic acid
Reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:37][OH:38].[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:24])[c:8]3[c:9]([O:22][CH3:23])[c:10](=[O:21])[n:11]([CH3:20])[c:12]([C:16](=[O:17])[O:18][CH3:19])[c:13]3[CH2:14][CH2:15]2)[cH:25][cH:26][c:27]1[F:28].[ClH:31].[Li+:30].[OH-:29].[OH2:39]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:24])[c:8]3[c:9]([O:22][CH3:23])[c:10](=[O:21])[n:11]([CH3:20])[c:12]([C:16](=[O:17])[OH:18])[c:13]3[CH2:14][CH2:15]2)[cH:25][cH:26][c:27]1[F:28]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b43132d0535c4da59e63d511e2081fed
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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