Hydrochloric Acid → N-(t-butoxy)-5-(4-chlorophenyl)4-(2,4-dichlorophenyl)thiazole-2-carboxamide

HRID 1143579Notes

Reaction equation

HRID 1143579 reaction equation
[C:57]([CH3:58])([CH3:59])([CH3:60])[O:61][NH2:62].[CH3:64][C:65]#[N:66].[CH3:67][CH2:68][O:69][C:70](=[O:71])[CH3:72].[CH:24]([N:25]([CH:26]([CH3:27])[CH3:28])[CH2:29][CH3:30])([CH3:31])[CH3:32].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:16]3[c:17]([Cl:23])[cH:18][c:19]([Cl:22])[cH:20][cH:21]3)[n:10][c:11]([C:13](=[O:14])[OH:15])[s:12]2)[cH:6][cH:7]1.[ClH:63].[P-:33]([F:34])([F:35])([F:36])([F:37])([F:38])[F:39].[n:40]1([O:41][C:42]([N:43]([CH3:44])[CH3:45])=[N+:46]([CH3:47])[CH3:48])[c:49]2[cH:50][cH:51][cH:52][cH:53][c:54]2[n:55][n:56]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:16]3[c:17]([Cl:23])[cH:18][c:19]([Cl:22])[cH:20][cH:21]3)[n:10][c:11]([C:13](=[O:15])[NH:62][O:61][C:57]([CH3:58])([CH3:59])[CH3:60])[s:12]2)[cH:6][cH:7]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 6342AcetonitrileHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 130500O-benzotriazol-1-yl-tetramethyluroniumHCID 2777907O-tert-butylhydroxylamineHCID 10045599HCID 10045599, compound

Product 1

HCID 86595683N-(t-butoxy)-5-(4-chlorophenyl)4-(2,4-dichlorophenyl)thiazole-2-carboxamide

Sources & evidence

ORD record
ord-9f9dff20a5cc45beb2b22baa7fecf0b8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…