Acetic Acid → 1'-(4-chlorophenyl)-6'-methoxy-5',7',8'-trimethyl-2',4'-dihydro-1'H-spiro[cyclobutane-1,3'-quinoline]
Reaction equation
[BH4-:12].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH2:58]([O:59][C:60](=[O:61])[CH3:62])[CH3:63].[CH3:1][C:2](=[O:3])[OH:4].[CH3:45][CH2:46][O:47][C:48]([CH3:49])=[O:50].[CH3:51][CH2:52][CH2:53][CH2:54][CH2:55][CH3:56].[Cl:14][c:15]1[cH:16][cH:17][c:18]([N:21]2[CH2:22][C:23]3([CH2:24][CH2:25][CH2:26]3)[CH:27]([OH:39])[c:28]3[c:29]([CH3:38])[c:30]([O:36][CH3:37])[c:31]([CH3:35])[c:32]([CH3:34])[c:33]32)[cH:19][cH:20]1.[Na+:13].[OH2:57].[OH:5][C:6]([C:7]([F:8])([F:9])[F:10])=[O:11]>>[Cl:14][c:15]1[cH:16][cH:17][c:18]([N:21]2[CH2:22][C:23]3([CH2:24][CH2:25][CH2:26]3)[CH2:27][c:28]3[c:29]([CH3:38])[c:30]([O:36][CH3:37])[c:31]([CH3:35])[c:32]([CH3:34])[c:33]32)[cH:19][cH:20]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-0aedeac8dd93442da726d53c3d54727d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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