Dimethylformamide → Ethyl 3-[2-amino-4-methyl-6-(oxan-4-ylamino)pyrimidin-5-yl]prop-2-enoate
Reaction equation
[C:24]([CH:25]=[CH2:26])(=[O:27])[O:28][CH2:29][CH3:30].[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[I:1][c:2]1[c:3]([NH:10][CH:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[n:4][c:5]([NH2:9])[n:6][c:7]1[CH3:8].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[cH:36]1[cH:37][cH:38][c:39]([P:40]([Pd:41]([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[P:80]([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)([c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)[c:105]2[cH:106][cH:107][cH:108][cH:109][cH:110]2)[cH:111][cH:112]1>>[c:2]1([CH:26]=[CH:25][C:24](=[O:27])[O:28][CH2:29][CH3:30])[c:3]([NH:10][CH:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[n:4][c:5]([NH2:9])[n:6][c:7]1[CH3:8]Participants
6
Sources & evidence
- ORD record
- ord-37adc72e593f48ee88942b4abdc0b44d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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