Hydrogen Bromide → N-benzyl-4-(p-fluorobenzoylmethyl)-4-piperidinyl hydrobromide

HRID 1145597Notes

Reaction equation

HRID 1145597 reaction equation
[Br:7][CH2:8][C:9](=[O:10])[c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1.[BrH:35].[CH2:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[N:25]1[CH2:26][CH2:27][C:28](=[O:31])[CH2:29][CH2:30]1.[CH2:32]([OH:33])[CH3:34].[Ce+3:2].[Cl-:1].[Cl-:3].[Cl-:4].[I-:6].[Na+:5].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[CH2:8]([C:9](=[O:10])[c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1)[C:28]1([Br:35])[CH2:27][CH2:26][N:25]([CH2:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[CH2:30][CH2:29]1

Participants

10

Reactant 9

HCID 260Hydrogen BromideHCID 312Chloride3×HCID 702EthanolHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 192201-Benzyl-4-piperidoneHCID 30165Iodide IonHCID 967492-Bromo-1-(4-fluorophenyl)ethan-1-oneHCID 114853Cerium(3+)

Product 1

HCID 89727103N-benzyl-4-(p-fluorobenzoylmethyl)-4-piperidinyl hydrobromide

Sources & evidence

ORD record
ord-613331afb68f416c8a681d69698ad3d1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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