1,2-Dichloroethane → 1-[4-[[4-(6,7-Dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]carbamoyl]-5-methyl-3-oxo-2-phenylpyrazol-1-yl]propan-2-yl 2-[(2-methylpropan-2-yl)oxycarbonylamino]acetate
Reaction equation
[C:43](=[O:44])([O:45][C:46]([CH3:47])([CH3:48])[CH3:49])[NH:50][CH2:51][C:52](=[O:53])[OH:54].[CH2:55]([Cl:56])[CH2:57][Cl:58].[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[c:17]([F:42])[cH:18][c:19]([NH:22][C:23](=[O:24])[c:25]4[c:26](=[O:41])[n:27](-[c:35]5[cH:36][cH:37][cH:38][cH:39][cH:40]5)[n:28]([CH2:31][CH:32]([CH3:33])[OH:34])[c:29]4[CH3:30])[cH:20][cH:21]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[CH3:59][N:60]([c:61]1[cH:62][cH:63][n:64][cH:65][cH:66]1)[CH3:67].[Cl:68][CH2:69][Cl:70]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[c:17]([F:42])[cH:18][c:19]([NH:22][C:23](=[O:24])[c:25]4[c:26](=[O:41])[n:27](-[c:35]5[cH:36][cH:37][cH:38][cH:39][cH:40]5)[n:28]([CH2:31][CH:32]([CH3:33])[O:34][C:52]([CH2:51][NH:50][C:43](=[O:44])[O:45][C:46]([CH3:47])([CH3:48])[CH3:49])=[O:53])[c:29]4[CH3:30])[cH:20][cH:21]3)[cH:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9cf0ef5d06454f15aafd3ec2e7b7bd3c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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