Tetrahydrofuran → 1-(2,4-Difluorophenyl)-1-(2-fluoro-3-(3-phenoxyphenyl)prop-1-enyl)cyclopropane
Reaction equation
[C:16]([O:17][CH2:20][C:21](=[CH:22][C:23]1([c:26]2[c:27]([F:33])[cH:28][c:29]([F:32])[cH:30][cH:31]2)[CH2:24][CH2:25]1)[F:34])(=[O:18])[CH3:19].[Mg:15].[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[cH:9][c:10]([Br:14])[cH:11][cH:12][cH:13]1.[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1>>[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[cH:9][c:10]([CH2:20][C:21](=[CH:22][C:23]2([c:26]3[c:27]([F:33])[cH:28][c:29]([F:32])[cH:30][cH:31]3)[CH2:24][CH2:25]2)[F:34])[cH:11][cH:12][cH:13]1Participants
5
Sources & evidence
- ORD record
- ord-cc93b599657a4a05b3c970b5969e7075
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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