Dimethylformamide → ethyl 4-(4-cyanophenyl)-3-[[3-(3-ethoxy-3-oxoprop-1-enyl)phenyl]methyl]-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4H-pyrimidine-5-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:36])[N:8]([c:26]3[cH:27][c:28]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:30][cH:31]3)[C:9]([CH3:25])=[C:10]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[CH:11]2[c:12]2[cH:13][cH:14][c:15]([C:18]#[N:19])[cH:16][cH:17]2)[cH:37][cH:38][cH:39]1.[C:40]([CH:41]=[CH2:42])(=[O:43])[O:44][CH2:45][CH3:46].[CH3:47][CH2:48][N:49]([CH2:50][CH3:51])[CH2:52][CH3:53].[CH3:54][N:55]([CH3:56])[CH:57]=[O:58]>>[c:2]1([CH:42]=[CH:41][C:40](=[O:43])[O:44][CH2:45][CH3:46])[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:36])[N:8]([c:26]3[cH:27][c:28]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:30][cH:31]3)[C:9]([CH3:25])=[C:10]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[CH:11]2[c:12]2[cH:13][cH:14][c:15]([C:18]#[N:19])[cH:16][cH:17]2)[cH:37][cH:38][cH:39]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-8d2a2e8a3dcc4c9181dee6989409d39f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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