Diisopropylamine → HCID 90945093, compound

HRID 1152426Notes

Reaction equation

HRID 1152426 reaction equation
[CH2:1]([C:2]#[CH:3])[N:4]1[CH2:5][CH2:6][CH2:7][CH2:8]1.[CH:9]([NH:10][CH:11]([CH3:12])[CH3:13])([CH3:14])[CH3:15].[Cu:57][I:58].[I:16][c:17]1[cH:18][cH:19][c:20]([C:23](=[CH:24][CH2:25][O:26][c:27]2[cH:28][c:29]([CH3:39])[c:30]([O:31][CH2:32][C:33](=[O:34])[O:35][CH3:36])[cH:37][cH:38]2)[c:40]2[cH:41][cH:42][c:43](-[c:46]3[s:47][c:48]([CH3:51])[cH:49][cH:50]3)[cH:44][cH:45]2)[cH:21][cH:22]1.[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1.[Pd:59]([Cl:60])[Cl:61].[c:62]1([P:63]([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[cH:76][cH:77][cH:78][cH:79][cH:80]1.[c:81]1([P:82]([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[cH:95][cH:96][cH:97][cH:98][cH:99]1>>[CH2:1]([C:2]#[C:3][c:17]1[cH:18][cH:19][c:20]([C:23](=[CH:24][CH2:25][O:26][c:27]2[cH:28][c:29]([CH3:39])[c:30]([O:31][CH2:32][C:33](=[O:34])[O:35][CH3:36])[cH:37][cH:38]2)[c:40]2[cH:41][cH:42][c:43](-[c:46]3[s:47][c:48]([CH3:51])[cH:49][cH:50]3)[cH:44][cH:45]2)[cH:21][cH:22]1)[N:4]1[CH2:5][CH2:6][CH2:7][CH2:8]1

Participants

8

Reactant 7

HCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 2996161-(Prop-2-yn-1-yl)pyrrolidineHCID 90739389HCID 90739389, compound

Product 1

HCID 90945093HCID 90945093, compound

Sources & evidence

ORD record
ord-9b3a4339387b4b02b49fb52feb366103
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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