Isopropanol → 5-Fluoro-2-(3-methylpiperazin-1-yl)pyrimidine
Reaction equation
[CH3:9][CH:10]1[NH:11][CH2:12][CH2:13][NH:14][CH2:15]1.[CH:16]([OH:17])([CH3:18])[CH3:19].[CH:20]([N:21]([CH2:22][CH3:23])[CH:24]([CH3:25])[CH3:26])([CH3:27])[CH3:28].[Cl:1][c:2]1[n:3][cH:4][c:5]([F:8])[cH:6][n:7]1>>[c:2]1([N:14]2[CH2:13][CH2:12][NH:11][CH:10]([CH3:9])[CH2:15]2)[n:3][cH:4][c:5]([F:8])[cH:6][n:7]1Participants
5
Sources & evidence
- ORD record
- ord-264f4f21088749debe2b7a4b80d7d9c0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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