Iodoethane → HCID 12813187, compound

HRID 1154985Notes

Reaction equation

HRID 1154985 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[C:11]([C:14]3[CH:15]=[C:16]([C:20]([F:23])([F:22])[F:21])[CH:17]=[CH:18][CH:19]=3)=[CH:10][NH:9]2)=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:30](I)[CH3:31]>C(O)C>[CH2:30]([N:9]1[CH:10]=[C:11]([C:14]2[CH:15]=[C:16]([C:20]([F:21])([F:23])[F:22])[CH:17]=[CH:18][CH:19]=2)[C:12](=[O:13])[N:8]1[C:5]1[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=1)[CH3:31]

Participants

5

Reactant 3

HCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 12813186HCID 12813186, compound

Product 1

HCID 12813187HCID 12813187, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 6 gram portion of 1-(4-fluorophenyl)-4-(α,α,α-trifluoro-3-tolyl)-3-pyrazolin-5-one (prepared according to the teaching outlined above) was mixed with 4 grams potassium carbonate and 15 ml. ethyl iodide in 100 ml. ethanol and refluxed overnight. The desired product was isolated in the usual way, yield 1.8 grams, m.p. approximately 92° C.

Sources & evidence

ORD record
ord-c65d23e4d7fd452bae7ce5383588fa87
Source dataset
uspto-grants-1981_11
Patent number
US04299614

Reaction notes

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