Iodoethane → HCID 12813191, compound

HRID 1154990Notes

Reaction equation

HRID 1154990 reaction equation
[C:1]1([C:7]2[C:11](=[O:12])[N:10]([C:13]3[CH:14]=[C:15]([C:19]([F:22])([F:21])[F:20])[CH:16]=[CH:17][CH:18]=3)[NH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:29](I)[CH3:30]>C(O)C>[CH2:29]([N:9]1[CH:8]=[C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[C:11](=[O:12])[N:10]1[C:13]1[CH:14]=[C:15]([C:19]([F:21])([F:22])[F:20])[CH:16]=[CH:17][CH:18]=1)[CH3:30]

Participants

5

Reactant 3

HCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 2766651HCID 2766651, compound

Product 1

HCID 12813191HCID 12813191, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2.2 grams of the pyrazolinone prepared above, 2 grams potassium carbonate, 25 ml. ethyl iodide and 25 ml. ethanol was refluxed for about 3 hours. The reaction mixture was worked up in the usual manner to yield an oil which was identified by NMR analysis as the desired product.

Workup

  1. customto yield an oil which

Sources & evidence

ORD record
ord-4be818947cf04778afaacb764b9a49d1
Source dataset
uspto-grants-1981_11
Patent number
US04299614

Reaction notes

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