反应详情

温度

5 °C

An amount of 2.27 g of 8-(2-methoxy-4-methylmercaptophenyl)-purine was dissolved in 20 ml of trifluoro acetic acid, and 1.2 ml of 30% hydrogen peroxide were added under cooling to 5° C. After stirring for 3 hours at room temperature and for 0.5 hours at 30° C., the reaction mixture was diluted with water and neutralized with potassium carbonate, and the residue obtained after evaporation was extracted with hot ethanol. The product obtained was purified over silicagel (eluate: methylene chloride/ethanol in a volume ratio of 19:1).

1. customthe residue obtained
2. customafter evaporation
3. extractionwas extracted with hot ethanol
4. customThe product obtained
5. customwas purified over silicagel (eluate: methylene chloride/ethanol in a volume ratio of 19:1)