Ethylmorpholine → HCID 54377318, compound

HRID 1156469Notes

Reaction equation

HRID 1156469 reaction equation
[CH:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7](Cl)=[O:8])=[CH:5][CH:4]=1)=O.[C:12](#[N:15])[CH:13]=C.C(N1CCOCC1)C>CC1C=CC(C)=CC=1.C([O-])(=O)C.[Pd+2].C([O-])(=O)C>[CH:7]([C:6]1[CH:10]=[CH:11][C:3]([CH:1]=[CH:13][C:12]#[N:15])=[CH:4][CH:5]=1)=[O:8]

Participants

6

Reactant 3

HCID 7525EthylmorpholineHCID 7855AcrylonitrileHCID 124246204-Formylbenzoyl chloride

Product 1

HCID 54377318HCID 54377318, compound

Reagents, catalysts & solvents 2

HCID 167845palladium(II) acetateCatalystHCID 7809P-XyleneSolvent

Procedure

The amounts of palladium acetate shown in Table 2 below, 6.74 g (40 millimols) of 4-formylbenzoyl chloride, 2.63 ml (40 millimols) of acrylonitrile and 5.12 ml (40 millimols) of N-ethylmorpholine, in 80 ml of p-xylene, are stirred for 5 hours at 120° C. The yields of 4-formylcinnamonitrile are shown in Table 2.

Sources & evidence

ORD record
ord-5d057e441cb345ca963285740d8fc5b2
Source dataset
uspto-grants-1982_06
Patent number
US04335054

Reaction notes

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