2-Aminothiazole → Indole

HRID 1159141Notes

Reaction equation

HRID 1159141 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7](NS(C)(=O)=O)[CH:8]=2)[CH:3]=[CH:2]1.C1(CBr)CC1.NC1SC=CN=1>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1

Participants

4

Reactant 3

HCID 21552-AminothiazoleHCID 81503BromomethylcyclopropaneHCID 18789669HCID 18789669, compound

Product 1

HCID 798Indole

Procedure

N-(1H-indole-6-yl)-methanesulfonamide, R5X=cyclopropyl-methylbromide; NH2A=2-aminothiazole

Sources & evidence

ORD record
ord-25c2b91308be40c8a57bf58942fb47f3
Source dataset
uspto-grants-2010_10
Patent number
US07812043B2

Reaction notes

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