1-Bromoheptane → HCID 20513493, compound

HRID 1164101Notes

Reaction equation

HRID 1164101 reaction equation
[H-].[Na+].[C:3]([CH:5]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([O:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[CH3:24])[C:12]=1[O:25][CH3:26])[C:6]([O:8][CH2:9][CH3:10])=[O:7])#[N:4].[CH2:27](Br)[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]>CN(C)C=O>[C:3]([C:5]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([O:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[CH3:24])[C:12]=1[O:25][CH3:26])([CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[C:6]([O:8][CH2:9][CH3:10])=[O:7])#[N:4]

Participants

5

Reactant 3

HCID 123691-BromoheptaneHCID 24758Sodium hydrideHCID 20513460HCID 20513460, compound

Product 1

HCID 20513493HCID 20513493, compoundYield 104.5%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent2×

Procedure

A suspension of sodium hydride (65%, 600 mg) in dimethylformamide (30 ml), a solution of ethyl 2-cyano-2-[2-methoxy-3-(o-tolyloxy)phenyl]acetate (5 g) in dimethylformamide (10 ml) and n-heptyl bromide (4.1 g) were treated in a similar manner to that of Example 25-(1) to give oily ethyl 2-cyano-2-[2-methoxy-3-(o-tolyloxy)phenyl]-n-nonanate (6.8 g).

Sources & evidence

ORD record
ord-23cd40f915484e2596494c5b7ac50537
Source dataset
uspto-grants-1983_01
Patent number
US04367238

Reaction notes

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