Hydrochloric Acid → HCID 14772120, compound

HRID 1164416Notes

Reaction equation

HRID 1164416 reaction equation
N[CH:2]1[C:24](=[O:25])[N:4]2[C:5]([C:11]([O:13][CH2:14][C:15]3[CH:20]=[CH:19][C:18]([N+:21]([O-:23])=[O:22])=[CH:17][CH:16]=3)=[O:12])=[C:6]([O:9][CH3:10])[CH2:7][S:8][C@H:3]12.FC(F)(F)S(OS(C(F)(F)F)(=O)=O)(=O)=[O:29].Cl>C(N(CC)CC)C>[O:29]=[C:2]1[C:24](=[O:25])[N:4]2[C:5]([C:11]([O:13][CH2:14][C:15]3[CH:20]=[CH:19][C:18]([N+:21]([O-:23])=[O:22])=[CH:17][CH:16]=3)=[O:12])=[C:6]([O:9][CH3:10])[CH2:7][S:8][C@H:3]12

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 67749Trifluoromethanesulfonic anhydrideHCID 70362009HCID 70362009, compound

Product 1

HCID 14772120HCID 14772120, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

4-Nitrobenzyl 7-amino-3-methoxy-3-cephem-4-carboxylate, trifluoromethanesulfonic anhydride, triethylamine and hydrochloric acid were reacted in the same manners as those of Examples 1-4 to give 4-nitrobenzyl 7-oxo-3-methoxy-3-cephem-4-carboxylate (monohydrate). Mp. 115°-120° C. (dec.).

Sources & evidence

ORD record
ord-37c01a5a30794046ac64f8062c5ec22c
Source dataset
uspto-grants-1983_01
Patent number
US04369312

Reaction notes

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