Hydrochloric Acid → HCID 14772126, compound

HRID 1164417Notes

Reaction equation

HRID 1164417 reaction equation
N[CH:2]1[C:23](=[O:24])[N:4]2[C:5]([C:10]([O:12][CH2:13][C:14]3[CH:19]=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][CH:15]=3)=[O:11])=[C:6]([Cl:9])[CH2:7][S:8][C@H:3]12.FC(F)(F)S(OS(C(F)(F)F)(=O)=O)(=O)=[O:28].Cl>C(N(CC)CC)C>[O:28]=[C:2]1[C:23](=[O:24])[N:4]2[C:5]([C:10]([O:12][CH2:13][C:14]3[CH:15]=[CH:16][C:17]([N+:20]([O-:22])=[O:21])=[CH:18][CH:19]=3)=[O:11])=[C:6]([Cl:9])[CH2:7][S:8][C@H:3]12

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 67749Trifluoromethanesulfonic anhydrideHCID 676435564-Nitrobenzyl 7-amino-3-chloro-3-cephem-4-carboxylate

Product 1

HCID 14772126HCID 14772126, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

4-Nitrobenzyl 7-amino-3-chloro-3-cephem-4-carboxylate, trifluoromethanesulfonic anhydride, triethylamine and hydrochloric acid were reacted in the same manners as those of Examples 1-4 to give 4-nitrobenzyl 7-oxo-3-chloro-3-cephem-4-carboxylate (monohydrate). Mp. 105°-106° C. (dec.).

Sources & evidence

ORD record
ord-cacf42a1fcbe4c7dadfe15747bb731b5
Source dataset
uspto-grants-1983_01
Patent number
US04369312

Reaction notes

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