Hydrochloric Acid → HCID 14772123, compound

HRID 1164418Notes

Reaction equation

HRID 1164418 reaction equation
N[CH:2]1[C:22](=[O:23])[N:4]2[C:5]([C:9]([O:11][CH2:12][C:13]3[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][CH:14]=3)=[O:10])=[CH:6][CH2:7][S:8][C@H:3]12.FC(F)(F)S(OS(C(F)(F)F)(=O)=O)(=O)=[O:27].Cl>C(N(CC)CC)C>[O:27]=[C:2]1[C:22](=[O:23])[N:4]2[C:5]([C:9]([O:11][CH2:12][C:13]3[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][CH:14]=3)=[O:10])=[CH:6][CH2:7][S:8][C@H:3]12

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 67749Trifluoromethanesulfonic anhydrideHCID 12775080p-Nitrobenzyl 7-amino-3-cephem-4-carboxylate

Product 1

HCID 14772123HCID 14772123, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

4-Nitrobenzyl 7-amino-3-cephem-4-carboxylate, trifluoromethanesulfonic anhydride, triethylamine and hydrochloric acid were reacted in the same manners as those of Examples 1-4 to give 4-nitrobenzyl 7-oxo-3-cephem-4-carboxylate. Mp. 141°-142° C. (dec.).

Sources & evidence

ORD record
ord-0eed7d053e2744b2be0d419fff040ea5
Source dataset
uspto-grants-1983_01
Patent number
US04369312

Reaction notes

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