Hydrochloric Acid → HCID 14772128, compound

HRID 1164419Notes

Reaction equation

HRID 1164419 reaction equation
N[CH:2]1[C:18](=[O:19])[N:4]2[C:5]([C:10]([O:12][CH2:13][C:14]([Cl:17])([Cl:16])[Cl:15])=[O:11])=[CH:6][CH:7]([CH3:9])[S:8][C@H:3]12.FC(F)(F)S(OS(C(F)(F)F)(=O)=O)(=O)=[O:23].Cl>C(N(CC)CC)C>[O:23]=[C:2]1[C:18](=[O:19])[N:4]2[C:5]([C:10]([O:12][CH2:13][C:14]([Cl:17])([Cl:16])[Cl:15])=[O:11])=[CH:6][CH:7]([CH3:9])[S:8][C@H:3]12

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 67749Trifluoromethanesulfonic anhydrideHCID 12834136HCID 12834136, compound

Product 1

HCID 14772128HCID 14772128, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2,2,2-Trichloroethyl 7-amino-2-methyl-3-cephem-4-carboxylate, trifluoromethanesulfonic anhydride, triethylamine and hydrochloric acid were reacted in the same manners as those of Examples 1-4 to give 2,2,2-trichloroethyl 7-oxo-2-methyl-3-cephem-4-carboxylate. Mp. 98° C.

Sources & evidence

ORD record
ord-031d91ab5b854a6c9ecb10c0c74e8be2
Source dataset
uspto-grants-1983_01
Patent number
US04369312

Reaction notes

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