Hydrochloric Acid → HCID 70463577, compound

HRID 1164421Notes

Reaction equation

HRID 1164421 reaction equation
N[CH:2]1[C:32](=[O:33])[N:4]2[C:5]([C:16]([O:18][CH:19]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[O:17])=[C:6]([CH2:9][S:10][C:11]3[S:12][CH:13]=[N:14][N:15]=3)[CH2:7][S:8][C@H:3]12.FC(F)(F)S(OS(C(F)(F)F)(=O)=O)(=O)=[O:37].Cl>C(N(CC)CC)C>[O:37]=[C:2]1[C:32](=[O:33])[N:4]2[C:5]([C:16]([O:18][CH:19]([C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)[C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)=[O:17])=[C:6]([CH2:9][S:10][C:11]3[S:12][CH:13]=[N:14][N:15]=3)[CH2:7][S:8][C@H:3]12

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 67749Trifluoromethanesulfonic anhydrideHCID 13470904HCID 13470904, compound

Product 1

HCID 70463577HCID 70463577, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Benzhydryl 7-amino-3-(1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylate, trifluoromethanesulfonic anhydride, triethylamine and hydrochloric acid were reacted in the same manners as those of Examples 1-4 to give benzhydryl 7-oxo-3-(1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylate.

Sources & evidence

ORD record
ord-26fc5c586b3e4c178a406a95b41b61bd
Source dataset
uspto-grants-1983_01
Patent number
US04369312

Reaction notes

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