Hydrochloric Acid → HCID 13881506, compound

HRID 1164441Notes

Reaction equation

HRID 1164441 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][CH2:10][CH2:11][CH:12]([NH:14][C:15]1[C:20]([CH3:21])=[CH:19][CH:18]=[CH:17][C:16]=1[CH3:22])[CH3:13].CC1C=CC=C(C)[C:25]=1[NH2:26].BrCCC(Br)C.Cl>>[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[N:9]1[CH2:10][CH2:11][CH:12]([CH3:13])[N:14]([C:15]2[C:20]([CH3:21])=[CH:19][CH:18]=[CH:17][C:16]=2[CH3:22])[C:25]1=[NH:26]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 68962,6-DimethylanilineHCID 78891,3-DibromobutaneHCID 20512466HCID 20512466, compound

Product 1

HCID 13881506HCID 13881506, compoundYield 45.6%

Procedure

1,3-Bis(2',6'-dimethylphenyl-amino)-butane, applied as starting substance, can be prepared e.g. by the method of Shapiro et al. (loc. cit.), utilizing 2,6-dimethylaniline and 1,3-dibromobutane as starting materials. The free base boils at 159°-160° C./0.1 mm Hg, and the hydrochloride melts at 178°-180° C. Yield: 45.6%.

Workup

  1. customcan be prepared e.g. by the method of Shapiro et al. (loc. cit.)

Sources & evidence

ORD record
ord-cf6897643a9d41da8702d0daf9b101cc
Source dataset
uspto-grants-1983_01
Patent number
US04369325

Reaction notes

Loading…