Triethylamine → Trimethylsilyl (4,4,7-trimethyl-thiochroman-6-yl) ethyne

HRID 116652Notes

Reaction equation

HRID 116652 reaction equation
[CH3:15][Si:16]([CH3:17])([CH3:18])[C:19]#[CH:20].[CH3:1][C:2]1([CH3:14])[CH2:3][CH2:4][S:5][c:6]2[cH:7][c:8]([CH3:13])[c:9]([Br:12])[cH:10][c:11]21.[CH3:64][CH2:65][N:66]([CH2:67][CH3:68])[CH2:69][CH3:70].[I-:21].[Pd+2:22].[Pd:23]([Cl:24])[Cl:25].[c:26]1([P:27]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[cH:40][cH:41][cH:42][cH:43][cH:44]1.[c:45]1([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:59][cH:60][cH:61][cH:62][cH:63]1>>[CH3:1][C:2]1([CH3:14])[CH2:3][CH2:4][S:5][c:6]2[cH:7][c:8]([CH3:13])[c:9]([C:20]#[C:19][Si:16]([CH3:15])([CH3:17])[CH3:18])[cH:10][c:11]21

Participants

8

Reactant 7

HCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 30165Iodide IonHCID 66111TrimethylsilylacetyleneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 156611176-Bromo-4,4,7-trimethylthiochroman

Product 1

HCID 15661126Trimethylsilyl (4,4,7-trimethyl-thiochroman-6-yl) ethyne

Sources & evidence

ORD record
ord-71d015ab19f44805951b70ee45d5d5af
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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