Ethyl Bromide → HCID 10198235, compound

HRID 1168417Notes

Reaction equation

HRID 1168417 reaction equation
[NH:1]1[C:5]2[C:6]3[C:11]([CH:12]=[CH:13][C:4]=2[NH:3][C:2]1=[O:14])=[CH:10][CH:9]=[CH:8][CH:7]=3.[H-].[Na+].Br[CH2:18][CH3:19]>>[CH2:18]([N:3]1[C:4]2[CH:13]=[CH:12][C:11]3[C:6]([C:5]=2[NH:1][C:2]1=[O:14])=[CH:7][CH:8]=[CH:9][CH:10]=3)[CH3:19]

Participants

4

Reactant 3

HCID 6332Ethyl BromideHCID 24758Sodium hydrideHCID 12205757HCID 12205757, compound

Product 1

HCID 10198235HCID 10198235, compound

Procedure

3-Ethyl-naphto[1,2-d]imidazolinone (1d) was prepared analogously by treatment of naphto[1,2-d]imidazolinone with sodium hydride (1.1 eq.) and bromoethane (1.1 eq.), successively. Yield after column-chromatographic workup: 2%. Mp. 240-242° C.

Workup

  1. customYield after column-chromatographic workup

Sources & evidence

ORD record
ord-565f310734664d8682e763dfb2b8ac46
Source dataset
uspto-grants-2003_09
Patent number
US06624186B2

Reaction notes

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