Sodium Iodide → HCID 102262612, compound

HRID 1168661Notes

Reaction equation

HRID 1168661 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([C:11]2[C:16](=[O:17])[N:15]([CH3:18])[C:13](=[O:14])[C:12]=2[O:19][CH3:20])=[CH:3]1.[Na+].[I-].[C:23](OCC)(=O)[CH3:24]>>[CH3:23][CH2:24][CH2:20][O:19][C:12]1[C:13](=[O:14])[N:15]([CH3:18])[C:16](=[O:17])[C:11]=1[C:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:2]([CH3:1])[CH:3]=1

Participants

4

Reactant 3

HCID 5238Sodium IodideHCID 8857Ethyl AcetateHCID 102262609HCID 102262609, compound

Product 1

HCID 102262612HCID 102262612, compound

Procedure

Into ethyl acetate was dissolved IM-8 (42 g) which was obtained as described above. NaI (42.5 g) was added. This mixture was refluxed for three hours. The reaction mixture was concentrated, and then refined with silica gel column chromatography (ethyl acetate/hexane) to obtain 36.3 g of IM-9.

Workup

  1. customwas obtained
  2. temperatureThis mixture was refluxed for three hours
  3. concentrationThe reaction mixture was concentrated

Sources & evidence

ORD record
ord-f1eb679a175c4a4595044e2ce17bcf31
Source dataset
uspto-grants-2003_09
Patent number
US06627099B2

Reaction notes

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